Prof. Zhanfen Qin received her Ph.D. from the Research Center for Eco-Environmental Sciences of the Chinese Academy of Sciences in 2002. After postdoctoral research in the Institute of Biophysics, she returned to the center in 2004. Her research has mainly focused on eco-toxicology and environmental toxicology, with great interests in endocrine disruption, reproductive and developmental toxicity and metabolism disorder. He has chaired a series of research projects supported by the National Key Research and Development Program of China, National Natural Science Foundation of China or other funds. She has published more than 100 papers in peer reviewed journals. Education: 2002, Ph.D, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences. Major: Environmental Sciences 1999, M.S., Institute of Blood Transfusion, Chinese Academy of Medical Sciences. Major: Medical microbiology 1995, B.S., Heibei University. Major: Environmental biology Professional Appointments: 2013.12-present, Professor, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing, China 2006.7-2013.12, Associate Professor, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing, China 2004.10-2006.6, Research Assistant, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing, China 2002.7-2004.9, Postdoctoral Research Fellow, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

Eco-toxicology and environmental toxicology

Yuan-Yuan Li, Yi-Ming Xiong, Xuan-Yue Chen, Jia-Yi Sheng, Lin Lv, Xing-Hong Li, Zhan-Fen Qin*. Extended exposure to tetrabromobisphenol A-bis(2,3-dibromopropyl ether) leads to subfertility in male mice at the late reproductive age. Archives of Toxicology, 2023 https://doi.org/10.1007/s00204-023-03589-y Yuan-Yuan Li, Yi-Ming Xiong, Shu-Yan Zhang, Jing-Lin Deng, Qiao Xue, Xing-Wang Hou, Wen-Bin Liu, Xing-Hong Li, Zhan-Fen Qin. Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) impairs postnatal testis development in mice: the Microtubule cytoskeleton as a sensitive target. Environment & Health, 2023, doi:10.1021/envhealth.3c00044 Yi-Ming Xiong, Yuan-Yuan Li*, Lin Lv, Xuan-Yue Chen, Xing-Hong Li, Zhan-Fen Qin. Postnatal exposure to low-dose tetrabromobisphenol A increases the susceptibility of mammal testes to chemical-induced spermatogenic stress in adulthood, Environment International, 2023, 171: 107683. Yuan-Yuan Li, Yi-Ming Xiong, Lin Lv, Xing-Hong Li, Zhan-Fen Qin*. Effects of low-dose bisphenol AF on mammal testis development via complex mechanisms: alterations are detectable in both infancy and adulthood, Archives of Toxicology 2022，96:3373–3383 Yuan-Yuan Li; Meng-Qi Dong; Yi-Ming Xiong; Qing Chang; Xuan-Yue Chen; Xu-Feng Fu; Xing-Hong Li; Zhan-Fen Qin*. Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events, Archives of Toxicology, 2022, 96:1881–1892. Yuan-Yuan Li, Jin-Bo Li, Man Cai, Zhan-Fen Qin*. Development of testis cords and the formation of efferent ducts in Xenopus laevis: differences and similarities with other vertebrates. Sexual Development, 2021:1-14. Man Cai, Yuan-Yuan Li, Min Zhu, Jin-Bo Li, Zhan-Fen Qin*, Evaluation of the effects of low concentrations of bisphenol AF on gonadal development using the Xenopus laevis model: A finding of testicular differentiation inhibition coupled with feminization. Environmental Pollution, 2020, 260: 113980. Yan-Ping Shen, Yuan-Yuan Li, Min Zhu, Jin-Bo Li, Zhan-Fen Qin*, Transcriptional changes caused by estrogenic endocrine disrupting chemicals in gonad-mesonephros complexes of genetic male Xenopus laevis: Multiple biomarkers for early detection of testis differentiation disruption. Science of the Total Environment, 2020, 726: 138522. Min Zhu, Yuan-Yuan Li, Yue Niu, Jin-Bo Li, Zhan-Fen Qin*. Effects of bisphenol A and its alternative bisphenol F on Notch signaling and intestinal development: A novel signaling by which bisphenols disrupt vertebrate development. Environmental Pollution, 2020, 263 (Pt B): 114443. Min Zhu, Yue Niu, Yuan-Yuan Li, Meng-Qi Dong, Jin-Bo Li, Ran Zeng, Zhan-Fen Qin*. Low concentrations of tetrabromobisphenol A disrupt Notch signaling and intestinal development in in vitro and in vivo models. Chemical Research in Toxicology. 2020, 33: 1418？1427. Min Zhu, Xiao-Ying Chen, Yuan-Yuan Li, Nuo-Ya Yin, Francesco Faiola, Zhan-Fen Qin*, Wu-Ji Wei*, Bisphenol F disrupts thyroid hormone signaling and postembryonic development in Xenopus laevis. Environmental Science & Technology, 2018, 52: 1602-1611. Ya-Xian Zhao, Yuan-Yuan Li, Xiao-Fei Qin, Qin-Qin Lou, Zhan-Fen Qin*. Accumulation of polybrominated diphenyl ethers in the brain compared with the levels in other tissues among different vertebrates from an e-waste recycling site. Environmental Pollution, 2016, 218: 1334-1341. Yin-Feng Zhang, Wei Xu, Qin-Qin Lou, Yuan-Yuan Li, Ya-Xian Zhao, Wu-Ji Wei, Zhan-Fen Qin*, Hui-Li Wang*, Jian-Zhong Li. Tetrabromobisphenol A disrupts vertebrate development via thyroid hormone signaling pathway in a developmental stage-dependent manner. Environmental Science & Technology. 2014, 48: 8227-8234.