EDUCATION BRACKGROUD
2002 Ph.D.        Graduate University of the Chinese Academy of Sciences
1991 B.S.        Peking University Health Science Center

WORK EXPERIENCE

03/2008-present        Professor, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences
11/2001-03/2008        Associate professor, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences.
07/1996-11/2001        Assistant professor, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences.
07/1991-07/1996        Research assistant, Research Center for Eco-Environmental Sciences, Chinese Academy of Science

Research Interest：

Development and application of in vitro bioassays for assessing biological effects posed by environmental pollutants and elusidating the mechnisms of action (MOA).

Selected Publications：

1. Yan Ye, Jiang Weiwei, Li Na, Ma Mei*, Wang Donghong, Wang Zijian*, Rao Kaifeng. Assessing genotoxicity of 16 centralized source waters in China by SOS/umu test and micronucleus test and initial identification of the potential genotoxicants by GC/MS method and QSAR Toolbox 3.0. Mutation Research/Genetic Toxicology and Environmental Mutagenesis , 2014, 763, 36–43
2.  Yan Ye, Jiang Weiwei, Li Na, Ma Mei*, Rao Kaifeng and Wang Zijian* Application of the SOS/umu test and highcontent in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles. Journal of Applied Toxicology, 2014, 34（12），1400-1408
3.  Rong Yang, Na Li, Mei Ma*, Zijian Wang, Combined effects of estrogenic chemicals with the same mode of action using an estrogen receptor binding bioassay, Environmental Toxicology and Pharmacology, 2014, 38（3），1382-1389
4.  RongYang, Na Li, Kaifeng Rao, Mei Ma*, ZijianWang, Combined action of estrogen receptor agonists and antagonists in two-hybridrecombinantyeast in vitro, Ecotoxicology and Environmental Safety , 2015, 111, 228–235
5.  Na Li, Weiwei Jiang, Mei Ma*, Donghong Wang, Zijian Wang，Chlorination by-products of bisphenol A enhanced retinoid X receptordisrupting effects, Journal of Hazardous Materials, 2016, 320, 289-295
6.  Ying nan Han, Na Li, YoshimitsuOda, Mei Ma*, Kaifeng Rao, ZijianWang, Wei Jin, Gang Hong, Zhiguo Li, Yi Luo，Evaluation of genotoxic effects of surface waters using a battery of Bioassays indicating different mode of action，Ecotoxicology and Environmental Safety, 2016, 133, 448–456
7.  ZH Huang; N Li; KF Rao; CT Liu; Y Huang; M Ma*; ZJ Wang*, Development of a data-processing method based on Bayesian k-means clustering to discriminate aneugens and clastogens in a high-content micronucleus assay, Human and Experimental Toxicology, 2017.3.15 , 37(3)：285~294
8.  Huang, Chao, Li, Na, Yuan, Shengwu, Ji, Xiaoya, Ma, Mei*, Rao, Kaifeng, Wang, Zijian, 2017. Aryl- and alkyl-phosphorus-containing flame retardants induced mitochondrial impairment and cell death in Chinese hamster ovary (CHO-k1) cells. Environmental Pollution, 230: 775-786.
9.  Han Yingnan, Ma Mei*, Li Na, Hou Rui, Huang Chao, Oda Yoshimitsu, Wang Zijian, 2018. Chlorination, chloramination and ozonation of carbamazepine enhance cytotoxicity and genotoxicity: Multi-endpoint evaluation and identification of its genotoxic transformation products. Journal of Hazardous Materials, 342(Supplement C): 679-688.
Huang C, Xu X, Wang D*, Ma M*, Rao K, Wang Z. The aryl hydrocarbon receptor (AhR) activity and DNA-damaging effects of chlorinated polycyclic aromatic hydrocarbons (Cl-PAHs) [J]. Chemosphere, 2018, 211: 640-647.
10. Yuan S, Huang C, Ji X, Ma M*, Rao K, Wang Z. Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression[J]. Ecotoxicology and Environmental Safety, 2018, 160: 1-9.
11. Huang Z , Li N , Rao K , Liu C , Wang Z *, Ma M*, In vitro Cytotoxicity and Genotoxicity Analysis of Ten Tannery Chemicals Using SOS/umu Tests and High-content In vitro Micronucleus Tests, Combinatorial Chemistry & High Throughput Screening, 2018, 21(4):262-270

Supported Projects：

1)  Mei Ma, “Influence of fulvic acid and colloid on partitioning hydrophobic organic contaminants and their bioconcentration in biota”, Grant No. 20207011, supported by National Natural Science Foundation of China,, 2002-2005
2)  Mei Ma, “The toxicity variation of organic pollutants during the drinking water treatment processes”, Grant No. 50378089, supported by National Natural Science Foundation of China, 2003-2006
3)  Mei Ma, “The distribution and the biological effects of endocrine disruptors in Beijing city ” , Grant No.8052018, supported by Beijing Natural Science foundation, 2004-2007
4)  Mei Ma, “Development of safety evaluation parameters of tap water and applied study of water quality insurance technologies for early warning sudden water pollution accident”, Grant No.D0605004040221, supported by Beijing municipal science and technology commission, 2005-2007
5)  Mei Ma, “New Technology study of using nuclear receptor superfamily for assessing the chemicals and environmental pollutants with different mode of endocrine disruptor action” National High Technology Research and Development Program of China (863 Program), Grant No. 2007AA06Z414, supported by the ministry of Science and Technology of the People’s Republic of China, 2007-2010
6)  Mei Ma, “Variation of endocrine disruptors with different mode of action in water treatment processes”, Grant No. 50778170, supported by National Natural Science Foundation of China, 2008-2010
7)  Mei Ma, “Molecular toxicology and Screening technology of toxic pollutants” Knowledge Innovation Program of the Chinese Academy of Sciences，Grant No. KZCX2-YW-Q02-05, supported by Chinese Academy of Sciences, 2009－2011
8)  Mei Ma, “High throughput bioassay technology for chemical toxicity evaluation” National High Technology Research and Development Program of China (863 Program) , Grant No. 2012AA06A302, supported by the ministry of Science and Technology of the People’s Republic of China , 2012-2015
9)  Mei Ma, “Standardization and application of health-effect evalution methods on water quality of the South-to North water diversion project, Grant No. Z171100004417025, supported by Beijing Municipal Science and Technology, 2017.4-2019.3
10)  Mei Ma, “Identification and control principle of risk factors for combined pollution of drinking water” Grant No. QYZDY-SSW-DQC004, supported by Chinese Academy of Sciences, 2016.10-2020.12

Honors：

Novel Bioassays Based on Nuclear Receptor Superfamily for Screening the Endocrine Disrupting Chemicals, second class prize of the Environmental protection science and Technology Award for 2013