2002-2006, B.S., Chemistry Department, Xiamen University, China 

　　2006-2011 Ph.D., Chemistry Department, Xiamen University, China 

　　2011-2013, Postdoctoral Fellow, Centre national de la recherche scientifique (CNRS), France 

　　2014-2015, Assistant professor, Research Center for Eco-Environmental Sciences (RCEES), Chinese Academy of Sciences 

　　2016-Present, Associate professor, Research Center for Eco-Environmental Sciences (RCEES), Chinese Academy of Sciences　　  

　　Dr. Ming Xu is an associate professor in the State Key Laboratory of Environmental Chemistry and Ecotoxicology in RCEES. His main research interests includes: (1) toxicology research of pollutants based on omics (proteomics, metallomics, etc.); (2) biological mechanism investigations on nanoparticles/microparticles. He has published 17 papers in peer-reviewed journals, including ACS Nano, Chemistry-A European Journal, Analytical Chemistry, etc. These papers have been cited more than 200 times. 

Toxicological study of typical environmental pollutants

(1) Xu, M.; Mohamed Soliman M. G.; Sun X.; Pelaz B.; Feliu N.; Parak W. J.;* Liu S.* Towards the prediction of protein corona formation and in vitro and in vivo interactions of gold nanoparticles based on their physicochemical properties. ACS Nano 2018, DOI: 10.1021/acsnano.8b04906.
(2) Zhu, J.; Xu, M.;* Gao, M.; Zhang, Z.; Xu, Y.; Xia T.; Liu, S.* Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents. ACS Nano 2017, 11, 2637-2651.
(3) Xu, M.; Zhu, J.; Wang, F.; Xiong, Y.; Wu, Y.; Wang, Q.; Weng, J.;* Zhang, Z.;* Chen, W.; Liu, S.* Improved In Vitro and In Vivo Biocompatibility of Graphene Oxide through Surface Modification: Poly(Acrylic Acid)-Functionalization is Superior to PEGylation. ACS Nano 2016, 10, 3267-3281.
(4) Zhu, J.;# Xu, M.;# Wang, F.; Gao, M.; Zhang, Z.; Xu, Y.; Chen, W.; Liu, S. Low-dose exposure of graphene oxide significantly increases metal toxicity to macrophages by altering their cellular priming state. Nano Research, 2018, 11, 4111-4122.
(5) Wang, X.; Cheng, W.; Yang, Q.; Niu, H.; Liu, Q.; Liu, Y.; Gao, M.; Xu, M.;* Xu, A.; Liu, S.; Huang, X.;* Du, Y. Preliminary investigation on cytotoxicity of fluorinated polymer nanoparticles. Journal of Environmental Sciences-China, 2018, 69, 217-226.
(6) Guo, W.; Zhang, J.; Li, W.; Xu, M.;* Liu, S.* Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review. Journal of Environmental Sciences-China, 2015, 34, 155-164.
(7) Xu, M.; Yang, L. M.; Wang, Q. Q.* Se-Hg Dual-element Labeling Strategy for Selectively Recognizing Selenoprotein and Selenopeptide. Chinese Journal of Analytical Chemistry, 2015, 43 (9), 1265-1271.
(8) Xu, M.; Bijoux H.; Gonzalez P.; Mounicou, S.* Investigating the response of cuproproteins from oysters (Crassostrea gigas) after waterborne copper exposure by metallomic and proteomic. Metallomics, 2014, 6 (2), 338-346.
(9) Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Non-denaturating isoelectric focusing gel electrophoresis for uranium–protein complexes quantitative analysis with LA-ICP MS. Analytical and Bioanalytical Chemistry, 2014, 406 (4), 1063-1072.
(10) Xu, M.; Frelon, S.; Simon, O.; Lobinski, R.; Mounicou, S.* Development of a non-denaturing 2D gel electrophoresis protocol for screening in vivo uranium-protein targets in Procambarus clarkii with laser ablation ICP MS followed by protein identification by HPLC–Orbitrap MS. Talanta, 2014, 128, 187-195.
(11) Xu, M.; Yang, L. M.; Wang, Q. Q.* Chemical interactions of mercury species and some transition and noble metals towards metallothionein (Zn7MT-2) evaluated using SEC/ICP-MS, RP-HPLC/ESI-MS and MALDI-TOF-MS. Metallomics, 2013, 5 (7), 855-860.
(12) Xu, M.; Yang, L. M.; Wang, Q. Q.* A way to probe the microenvironment of free sulfhydryls in intact proteins with a series of monofunctional organic mercurials. Chemistry - A European Journal, 2012, 18 (44), 13989-13993.
(13) Xu, M., Yan, X. W., Xie, Q. Q., Yang, L. M., Wang, Q. Q.* Dynamic labeling strategy with 204Hg-isotopic methylmercurithiosalicylate for absolute peptide and protein quantification. Analytical Chemistry, 82 (5), 1616-1620, 2010.
(14) Xu, M., Deng, G. F., Liu, S. S., Chen, S., Cui, D., Yang, L. M., Wang, Q. Q.* Free cadmium ions released from CdTe-based nanoparticles and their cytotoxicity on Phaeodactylum tricornutum. Metallomics, 2 (7), 469-473, 2010.
(15) Xu, M., Yang, L. M., Wang, Q. Q.* Quantification of selenium-tagged proteins in human plasma using species-unspecific isotope dilution ICP-DRC-qMS coupled on-line with anion exchange chromatography. Journal of Analytical Atomic Spectrometry, 23 (11), 1545-1549, 2008.